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Home » Bharat Biotech to Co-Develop Broad Spectrum Anti-Microbial Vaccine

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Bharat Biotech to Co-Develop Broad Spectrum Anti-Microbial Vaccine

NewsFacts Bureau
Last updated: September 11, 2024 1:02 pm
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Bharat Biotech to Co-Develop, and Commercialise Broad Spectrum Anti-Microbial Vaccine : Photo Credit Bharat Biotech
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Hyderabad, India, 11th September 2024 – Bharat Biotech, today announced a collaboration with Alopexx, Inc., for the co-development and commercialization of Alopexx’s proprietary broad-spectrum anti-microbial vaccine, AV0328, in India and other low-income and lower middle-income countries.

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Bharat Biotech’s New Vaccine to reduce anti-microbial resistanceKnow more about AV0328 – Anti Microbial Vaccine

As part of the collaboration, the companies will co-develop and commercialize AV0328, a synthetic vaccine targeting poly N-acetyl glucosamine (PNAG), in India and other licensed territories. Alopexx would be entitled to a one-time upfront payment and milestone payments, as well as royalties on future sales of AV0328 in the licensed territories.

Bharat Biotech is a pioneering biotechnology company known for its world-class research and development and manufacturing capabilities, and Alopexx, Inc., a clinical-stage biotechnology company focused on developing novel, broad-spectrum immune-mediated therapeutics for the prevention and treatment of bacterial, fungal, and parasitic infections.

Bharat Biotech’s New Vaccine to reduce anti-microbial resistance

Bharat Biotech to develop anti-microbial vaccine
Bharat Biotech Plant at Genome Valley – photo credit Bharat Biotech

Dr. Krishna Ella, Executive Chairman of Bharat Biotech, commented, “We are proud to collaborate with Alopexx to bring AV0328 to the regions where it is most needed. Our goal is to develop solutions to reduce anti-microbial resistance through vaccination. This collaboration aligns with our mission to provide safe, affordable, and high-quality vaccines to combat infectious diseases globally.”

“We are excited to enter into this collaboration with Bharat Biotech,” said Dr. Daniel Vlock, CEO of Alopexx. “To partner with a company with such vast experience and expertise in vaccine development is a significant validation of the value and potential of Alopexx’s technology. This collaboration brings us one step closer to addressing the critical need for affordable, broad-spectrum antimicrobial solutions, especially in low-and middle-income countries.”

Dr. Vlock added, “We also deeply appreciate the collaborative support provided by Bharat Biotech. This support is not only crucial for the advancement of AV0328, but will also significantly bolster our overall clinical programs. The broad and breakthrough potential of our platforms in treating a wide array of bacterial, fungal, and parasitic infections represents a transformative approach to combating infectious diseases on a global scale.”

Know more about AV0328 – Anti Microbial Vaccine

AV0328 is a synthetic vaccine designed to target poly N-acetyl glucosamine (PNAG), a substance found on the surface of a wide range of bacterial, fungal, and parasitic pathogens. In pre-clinical studies, targeting PNAG has shown effectiveness in preventing and treating infections caused by over 15 different pathogens. A phase I, first-in-human trial has been completed, demonstrating that AV0328 is well-tolerated with no serious adverse events observed.

The vaccine induced antibodies capable of killing a wide range of PNAG-expressing pathogens, reaffirming its potential as a broad-spectrum antimicrobial solution.

TAGGED: Anti Microbial Vaccine, AV0328, Bharat Biotech, Dr. Krishna Ella, Healthcare, immune medication, Infectious Diseases, therapeutics, Vaccine
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