thenewsfacts.com
  • Home
  • Latest News
  • Trending News
  • Entertainment
  • Technology
  • Sports
  • Business
  • Health
thenewsfacts.comthenewsfacts.com
Font ResizerAa
Search
  • Home
  • Latest News
  • Trending News
  • Entertainment
  • Technology
  • Sports
  • Business
  • Health
Follow US
© thenewsfacts : All Rights Reserved.

Home » A new gene holds great promise to halt fungal infection in immuno-compromised people

Health

A new gene holds great promise to halt fungal infection in immuno-compromised people

TheNewsFacts
Last updated: August 25, 2022 4:17 pm
TheNewsFacts
Share
A new gene holds great promise to halt fungal infection in immuno-compromised people
SHARE

A recently discovered gene may hold the key to halting the spread of Candidiasis fungus. Patients in the intensive care unit (ICU), those with cancer, and those undergoing immunosuppressive therapy are frequently affected by candidiasis.

The CSA6 gene has been found in Candida albicans, a fungus notorious for producing high rates of morbidity and mortality over the course of cancer treatment or in immunosuppressed situations like AIDS.

When an immune system is compromised, a fungus that normally lives in the mucosal linings of the gastrointestinal and urogenital tracts of healthy people develops into a pathogen that compromises the host’s defences and can lead to both superficial infections and potentially fatal systemic infections.

New study on Candidiasis Fungal Infection Prevention looks promising

In a recent study conducted in collaboration with Christophe d’Enfert’s group at the Institut Pasteur in Paris, France, and Professor Kaustuv Sanyal’s group at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bangalore, India, authors carried out a large-scale screen to identify regulators of chromosome stability in C. albicans, a clinically relevant fungal model system.

Individually examining the impact of overexpression of more than a thousand C. albicans genes on genome stability, the authors from JNCASR, an autonomous institute of the Department of Science and Technology (DST), were able to pinpoint a group of six chromosome stability (CSA) genes that are crucial for preserving genome integrity.

The sixth CSA gene, designated CSA6, encoded for a protein that was crucial for the viability of C. albicans, whereas five of the CSA genes discovered in the study are known to be significant for cell division in other species. They discovered that Csa6 played a crucial role in controlling cell cycle progression, and that its overexpression or deletion resulted in a decrease in the development of C. albicans cells.

The work, which was published in the journal Nature Communications, is the first to provide a thorough screen of C. albicans, a human fungal infection. It finds and clarifies the roles of a unique chromosomal stability regulator that is only seen in a subset of therapeutically significant human fungal infections.

Additionally, it offers a methodical approach for locating genes whose by-products may be used to treat fungal infections by having fewer negative effects on people. Small molecule modulators that change the expression levels of the Csa6 gene therefore present prospective therapy options with no adverse effects in humans.

TAGGED: Fungus infection, Fungus treatment, Immunosuppressive, New Gene, New Molecule
Share This Article
Twitter Email Copy Link Print
Previous Article Nigeria to avert 50,000 child deaths annually with ROTAVAC vaccine Nigeria to avert 50,000 child deaths annually with ROTAVAC vaccine
Next Article NASA's new study supports Einstein's theory of gravity, but the mystery of dark energy persists NASA’s new study supports Einstein’s theory of gravity, but the mystery of dark energy persists

Your Trusted Source for Accurate and Timely Updates!

We're committed to providing accurate and unbiased news as it unfolds, earning the trust of a large audience. Stay informed with our news updates on the latest events and trends, keeping you ahead of the curve.
FacebookLike
TwitterFollow
InstagramFollow

Popular Posts

Vietnamese Tycoon Truong My Lan Faces Death Penalty in an Unprecedented Fraud Case

April 12: In a landmark trial that captivated the nation, 67-year-old Vietnamese property developer Truong My…

By TheNewsFacts

Uttarakhand Avalanche: 55 Workers Trapped, 14 Rescued So Far

March 1, 2025: Uttarakhand Avalanche: 14 More Rescued, 8 Still Trapped in Chamoli Rescue operations…

By TheNewsFacts

Total Lunar Eclipse 2022: One last time to watch it today, and how

The 2022 total lunar eclipse that will occur today is the last one for the following three…

By TheNewsFacts

You Might Also Like

Rotavirus Vaccine
HealthLatest News

Dr. Cyriac Exposes Science Illiteracy in Misleading Report on Rotavirus Vaccine

By TheNewsFacts
Covid
Health

New FLiRT-ing COVID Variant Emerges in Thailand: Public Urged to Mask Up

By NewsFacts Bureau
High Protein Risk
Health

High Protein Diets May Increase Heart Attack Risk, Study Finds

By SK Panicker
Bipolar Disorder
Health

Understanding Bipolar Disorder: A Rollercoaster of Emotions

By TheNewsFacts
thenewsfacts thenewsfacts

About US


TheNewsFacts: Brings you the interesting facts, news facts and updates from India an the world across politics, tech, entertainment, business, tending, and more. We deliver what you love to read.
Top Categories
  • Latest News
  • Trending News
  • Paris Olympics 2024
  • Sports
  • Entertainment
  • Business
  • Technology
Usefull Links
  • About The News Facts
  • Latest News
  • Privacy Policy
  • Editorial Policy
  • Disclaimer
  • Contact Us
Follow us
Facebook Twitter Instagram

© thenewsfacts. All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?